Arabia: Early Arab traders, depicted heading to India and the East, c. 600—700 CE.

The original Spice Trade, or 'Incense Route', from the Mediterranean to India and the East was closed off to Europeans due to the spread of Islam after the Prophet Muhammad's death in 632 CE. Traders from the Arabian world controlled overland and sea routes from India to the Levant and Venice. Arabs monopolized trade in drugs, hemp, opium, incense and spices for centuries until the Ottoman Turks broke their stranglehold on Eastern trade in 1453.

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