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Afghanistan: A gold stater of the Seleucid king Antiochus I Soter minted at Ai-Khanoum, c. 275 BCE. Obverse: Diademed head of Antiochus. Reverse: Nude Apollo seated on an omphalos (religious stone), leaning on bow and holding two arrows. Greek legend: BAΣ

Ai-Khanoum or Ay Khanum ( 'Lady of the Moon' in Uzbek, probably the historical Alexandria on the Oxus, also possibly named Eucratidia), was founded in the 4th century BCE, following the conquests of Alexander the Great and was one of the primary cities of the Greco-Bactrian kingdom.

The city is located in Kunduz Province northern Afghanistan, at the confluence of the Oxus river (today's Amu Darya) and the Kokcha river. Ai Khanoum was one of the focal points of Hellenism in the East for nearly two centuries, until its destruction by nomadic invaders around 145 BCE about the time of the death of Eucratides.

The site was excavated through archaeological searches by a French mission under Paul Bernard between 1964 and 1978, as well as by Russian archaeologists. These researches had to be abandoned with the beginning of the Soviet war in Afghanistan, during which the site was looted and used as a battleground, leaving very little of the original material.